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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SETD1B
All Species:
5.15
Human Site:
T973
Identified Species:
8.72
UniProt:
Q9UPS6
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPS6
NP_055863.1
1923
208732
T973
R
K
E
P
P
D
T
T
S
S
G
D
Q
K
R
Chimpanzee
Pan troglodytes
XP_523492
1707
185692
L861
K
L
K
E
P
G
L
L
S
L
V
D
W
A
K
Rhesus Macaque
Macaca mulatta
XP_001092031
624
66545
Dog
Lupus familis
XP_543382
1925
209302
A976
R
K
E
P
P
D
T
A
S
A
G
D
Q
K
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFT2
1985
215333
A964
R
K
E
P
P
D
T
A
S
S
G
D
Q
K
R
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510235
695
75024
Chicken
Gallus gallus
Q5F3P8
2008
223067
A957
R
K
E
P
P
E
A
A
S
A
G
D
Q
K
R
Frog
Xenopus laevis
Q66J90
1938
216239
A922
R
K
E
P
P
D
A
A
L
A
G
D
Q
K
R
Zebra Danio
Brachydanio rerio
Q1LY77
1844
204122
T902
R
K
Q
P
P
E
P
T
S
T
S
D
N
K
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001015221
1641
188364
S815
V
A
D
F
Q
S
Y
S
S
I
G
L
R
A
A
Honey Bee
Apis mellifera
XP_395451
1406
159180
V581
I
N
G
V
L
N
R
V
V
N
E
L
K
Q
I
Nematode Worm
Caenorhab. elegans
Q18221
1507
171664
E682
P
E
K
P
S
L
S
E
R
F
S
G
I
F
G
Sea Urchin
Strong. purpuratus
XP_791552
1963
220543
D923
D
Q
Q
T
A
S
R
D
T
S
P
I
S
D
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q8X0S9
1313
145607
P488
H
E
Y
V
P
V
M
P
T
T
V
A
H
M
K
Conservation
Percent
Protein Identity:
100
37.3
27.9
91.9
N.A.
87.7
N.A.
N.A.
23.1
61.5
55
51
N.A.
24.7
23.9
22.3
21.3
Protein Similarity:
100
50.3
28.8
93.9
N.A.
90.2
N.A.
N.A.
26.7
71.1
66.6
63.6
N.A.
39.4
38.6
35.2
35.2
P-Site Identity:
100
20
0
86.6
N.A.
93.3
N.A.
N.A.
0
73.3
73.3
60
N.A.
13.3
0
6.6
6.6
P-Site Similarity:
100
40
0
93.3
N.A.
93.3
N.A.
N.A.
0
86.6
80
80
N.A.
33.3
26.6
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
22.2
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
35.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
8
0
15
29
0
22
0
8
0
15
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
8
0
0
29
0
8
0
0
0
50
0
8
0
% D
% Glu:
0
15
36
8
0
15
0
8
0
0
8
0
0
0
0
% E
% Phe:
0
0
0
8
0
0
0
0
0
8
0
0
0
8
0
% F
% Gly:
0
0
8
0
0
8
0
0
0
0
43
8
0
0
15
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
8
0
0
0
0
0
0
0
0
8
0
8
8
0
8
% I
% Lys:
8
43
15
0
0
0
0
0
0
0
0
0
8
43
15
% K
% Leu:
0
8
0
0
8
8
8
8
8
8
0
15
0
0
0
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
0
0
8
0
% M
% Asn:
0
8
0
0
0
8
0
0
0
8
0
0
8
0
0
% N
% Pro:
8
0
0
50
58
0
8
8
0
0
8
0
0
0
0
% P
% Gln:
0
8
15
0
8
0
0
0
0
0
0
0
36
8
0
% Q
% Arg:
43
0
0
0
0
0
15
0
8
0
0
0
8
0
43
% R
% Ser:
0
0
0
0
8
15
8
8
50
22
15
0
8
0
0
% S
% Thr:
0
0
0
8
0
0
22
15
15
15
0
0
0
0
0
% T
% Val:
8
0
0
15
0
8
0
8
8
0
15
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% W
% Tyr:
0
0
8
0
0
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _